Dobrawa Napierala's Research Interests

Dr. Napierala’s research is focused on molecular determinants of disturbed development and homeostasis of mineralizing tissues, and in regeneration and repair of these tissues. Dr. Napierala studies diseases associated with defective endochondral ossification, formation of dental tissues, bone mineral density and ectopic mineralization. She is interested in the role of the TRPS1 transcription factor in skeletal and dental development and homeostasis, and in the mineralization process. Related to this, Dr. Napierala studies the phosphate signaling pathway in mineralizing cells and the biogenesis of matrix vesicles, which play important role in the initiation of the mineralization process of bone, cartilage and dentin, and have been implicated in vascular calcification.

View Dr. Napierala's publications