Major projects include:
Pittsburgh Orofacial Cleft Studies
Pittsburgh Orofacial Cleft (POFC) Studies investigate genetic contributions to orofacial clefting—with an emphasis on related sub-clinical phenotypes—in families from multiple national and international sites.
Oral Health Studies
Oral Health Studies at the CCDG investigate genetic, microbial, and behavioral risk factors for early childhood caries and other oral health pathologies.
Genomic Studies
The CCDG is a collaborator in several large-scale, National Institutes of Health (NIH)-sponsored genomic studies including the Gene Environment Association Studies Initiative (GENEVA) and genome-wide association study (GWAS) initiatives to better understand the genetics of dental caries and oral clefts.
The 3D Facial Norms Study
The 3D Analysis of Normal Facial Variation Study (NIH/NIDCR Grant U01-DE020078) was a collaborative initiative led by Drs. Weinberg and Marazita, involving investigators at Seattle Children’s Research Institute, the University of Texas Health Science Center at Houston, and the University of Iowa.
Computational Methods Development
Other CCDG Collaborations
CCDG faculty provide statistical genetic and other expertises to investigators around the world.
